Institutional Review Board

918-453-5000 ext. 5187
1325 East Boone Street Tahlequah, OK 74464

Submit a Proposal

The Cherokee Nation has a long history of supporting biomedical, social, educational, and behavioral research. This is especially true when research studies are proposed in a culturally sensitive manner and when it fills a gap in knowledge or services provided.

Applications for research must be submitted by the Principal Investigator of a research project, 10 business days before the CN IRB board meeting.

At the bottom of this page, you will find all the necessary documents needed to complete and submit your application to us.

Key things to know:

  • The CN IRB meets every 2nd Wednesday of the month
  • Any Adverse Events should be submitted directly to the CN IRB through our email IRB@cherokee.org
  • You can also submit any study renewals, amendments and/or study closures through this page.
  • Some research may require multiple IRB's approvals before activities can begin.
  • You will need a Tribal letter of support for any proposal submitted.

For more information and help please review the Guidance page or contact us.


  • Fillable HIPAA form
    Cherokee Nation authorization to access, use or disclose protected health information (PHI) that identifies you for a research study.
  • HIPPA Tree
    Determining when HIPAA applies to health research.
  • Informed Consent Guide
    Informed Consent must be obtained for all types of human subjects research.
  • Lay Summary Guide
    Summary of research project goals, activities, and findings, that is used to explain complex scientific theories and technical terms to non-scientific people.
  • Proposal Application
    Application to submit a new research proposal to the Institutional Review Board.
  • Renewal Application
    Renewal application for renewing your research proposal with the Institutional Review Board.
  • Tribal Research Guide
    Guide on conducting research within tribal communities within the Cherokee Nation.